This formulation is a synergistic broad-spectrum antibiotic veterinary oral powder combining Doxycycline Hydrochloride I.P. and Neomycin Sulphate I.P., each equivalent to 100 mg of their respective active forms per gram of powder. Doxycycline is a long-acting tetracycline antibiotic with high tissue penetration and a broad antibacterial spectrum, while Neomycin is an aminoglycoside effective against many Gram-negative and some Gram-positive bacteria.

•  Appearance: Free-flowing, fine, light yellow to off-white powder

•  Identification: Conforms to I.P. standards for Doxycycline and Neomycin by HPLC and UV spectrophotometry

•  Assay:

           o  Doxycycline HCl I.P.: Equivalent to 100 mg Doxycycline per gram

           o  Neomycin Sulphate I.P.: Equivalent to 100 mg Neomycin per gram

• Loss on Drying: Not more than 5.0%

• pH (1% w/v solution): Between 3.5 and 5.5

•  Microbial Limits: Conforms to veterinary I.P. microbiological standards

•  Heavy Metals: Within acceptable limits

•  Uniformity: Consistent drug distribution throughout the bulk powder

•  Shelf Life: Minimum 24 months under recommended storage conditions

Indicated for the treatment, prevention, and control of bacterial infections in poultry and livestock, particularly:

•  Gastrointestinal infections

•  Respiratory tract infections

•  Secondary bacterial complications of viral infections

•  Mixed infections caused by Doxycycline- and Neomycin-sensitive organisms such as E. coli, Mycoplasma, Salmonella, Pasteurella, and Staphylococcus spp.

•  Route: Oral, through feed or drinking water

•  General Dosage:

          o  Poultry: 1 gm per litre of drinking water or 1 kg feed for 3–5 days

         o  Livestock (Cattle, Sheep, Goats, Pigs): 10–20 mg per kg body weight per day, divided into two doses for 3–5 days

•  Dosage may vary depending on the species, severity of infection, and veterinarian's discretio

•  Veterinary Oral Powder

•  Available pack sizes: 100 gm, 250 gm, 500 gm, 1 kg

•  Fine, palatable, easy-mixing powder for use in feed or water

•  Broad-spectrum antibacterial coverage from two synergistic antibiotics

•  Highly effective against both systemic and enteric bacterial infections

•  Excellent bioavailability and deep tissue penetration (Doxycycline)

•  Minimal resistance development when used as directed

•  Easy administration via feed or water

•  Enhances animal health, growth, and production outcomes

•  Reduces mortality and morbidity due to bacterial infections in poultry and livestock

•  Rare gastrointestinal disturbances may occur, such as nausea or diarrhoea

•  Prolonged use may alter gut microflora and lead to superinfection

•  Neomycin may have nephrotoxic effects at very high doses or prolonged exposure

•  Hypersensitivity reactions are rare but possible

•  Do not use in animals with known hypersensitivity to tetracyclines or aminoglycosides

•  Meat: Minimum 7 days from last treatment

•  Milk: Minimum 3 days (if used in lactating animals)

•  Eggs (for laying hens): Minimum 7 days

•  Observe exact withdrawal periods as per regulatory guidelines to prevent antibiotic residues in animal products

•  Store in a dry, cool place below 30°C

•  Protect from sunlight, moisture, and excessive heat

•  Seal container tightly after use

•  Use personal protective equipment when handling the powder

• Keep out of reach of children, pets, and unauthorized personnel

•  Dispose of packaging responsibly and do not reuse containers

•  HS Code: 2941.90 — Other antibiotics and their derivatives

•  HSN Code (India): 2941 — Antibiotics and other antibacterial veterinary formul

•  Use only under the supervision of a registered veterinarian

•  Not to be used in animals with impaired liver or kidney function unless advised by a veterinarian

•  Avoid use in animals intended for breeding without veterinary advice

•  Rotate antibiotics periodically to reduce resistance development

•  Do not mix with other veterinary drugs without professional guidance

•  Ensure animals have access to adequate hydration during treatment

•  Follow manufacturer’s label instructions strictly for dosage and withdrawal

•  Veterinary Use Only

•  Not for human consumption or use

•  Antibiotics such as Doxycycline and Neomycin are classified for veterinary application with specific residue and withdrawal guidelines to protect human health

•  Ensure that treated animals do not enter the human food chain before completion of the specified   withdrawal period

•  Accidental human exposure (inhalation or ingestion) should be avoided. Seek immediate medical attention in case of exposure

Q: What is Doxycycline Hydrochloride (DCHC)?

A: Doxycycline Hydrochloride (DCHC) is a tetracycline-class antibiotic effective against many Gram-positive and Gram-negative bacteria. It works by inhibiting bacterial protein synthesis.

Q: What is Neomycin Sulphate (NS)?

A: Neomycin Sulphate (NS) is an aminoglycoside antibiotic effective mainly against Gram-negative bacteria. It acts by binding to bacterial ribosomes and preventing protein formation.

Q: Can this powder be given to poultry and livestock?

A: Yes, it is suitable for poultry (broilers, layers) and livestock such as cattle, goats, sheep, and pigs.

Q: How do I administer the powder to animals?

 A: Mix the powder with feed or dissolve in drinking water according to the dosage instructions provided by a veterinarian.

Q: Is there a withdrawal period?

A: Yes, meat and egg withdrawal is at least 7 days, and for milk, it is 3 days. Always follow label and regulatory instructions.

Q: Can I use this in pregnant animals?

A: Use only if prescribed by a veterinarian. Avoid in the first trimester unless clearly needed.

Q: How should the product be stored?

 A: Store below 30°C in a dry, cool place, away from sunlight and moisture. Keep sealed tightly after use