Levamisole Hydrochloride I.P. 30% w/w veterinary oral powder is a potent broad-spectrum anthelmintic formulation designed for oral administration to livestock and poultry. Levamisole belongs to the imidazothiazole class of antiparasitic agents, known for its effectiveness against both mature and immature stages of gastrointestinal and pulmonary nematodes (roundworms).

This water-soluble powder acts as a nicotinic acetylcholine receptor agonist, causing spastic paralysis in nematodes, leading to their expulsion from the body. It also exhibits immunomodulatory effects, making it useful in disease resistance management.

•  Appearance: Fine, white to off-white free-flowing powder

•  Identification: Confirms to I.P. specifications for Levamisole Hydrochloride using titration and HPLC methods

•  Assay: 30% w/w Levamisole Hydrochloride I.P.

•  Solubility: Freely soluble in water

•  Loss on Drying: Not more than 5.0%

•  pH (1% aqueous solution): Between 4.5 and 6.5

•  Microbial Load: Complies with veterinary pharmacopeial microbial standards

•  Heavy Metals: Within acceptable I.P. limits

•  Uniformity: Homogeneous distribution of drug in all dosage sizes

•  Shelf Life: Minimum 24 months under recommended storage conditions

Levamisole 30% w/w oral powder is indicated for the treatment and control of gastrointestinal and pulmonary nematode infestations in livestock and poultry, including:

•  Ascaridia spp.

•  Haemonchus contortus

•  Trichostrongylus spp.

•  Ostertagia spp.

•  Oesophagostomum spp.

•  Bunostomum spp.

•  Nematodirus spp.

•  Dictyocaulus spp. (lungworms)

•  Route: Oral, via feed or drinking water

•  Poultry: 20 mg Levamisole HCl per kg body weight (approx. 0.067 g of 30% powder per kg BW)

•  Cattle, Sheep, Goats, Pigs: 7.5 mg Levamisole HCl per kg body weight (approx. 0.025 g of 30% powder per kg BW)

• Administration Frequency: Single dose, repeat as per veterinarian's guidance or routine deworming schedule

•  Ensure uniform distribution when mixing with feed or water

•  Veterinary oral powder

•  Pack sizes: 100 gm, 250 gm, 500 gm, 1 kg, 5 kg

•  Easy-to-mix, water-soluble formulation for practical field use

•  Highly effective against a broad spectrum of nematodes

•  Acts quickly by causing paralysis and expulsion of worms

• Boosts immune response due to immunostimulant properties

•  Ideal for mass deworming programs

•  Safe for use in food-producing animals when used as directed

•  Rare and generally mild at therapeutic doses

•  Possible transient side effects include salivation, excitement, or mild gastrointestinal upset

•  Overdosage may lead to cholinergic symptoms (e.g., muscle tremors, convulsions)

•  Toxicity more likely in debilitated or undernourished animals

•  Stop treatment and consult a veterinarian if adverse reactions are observed

•  Meat: Minimum 7 days after last dose

•  Milk: Minimum 3 days in lactating animals

•  Always adhere to regulatory withdrawal periods to avoid drug residues in animal-derived food products

•  Store below 30°C in a cool, dry, well-ventilated area

•  Protect from direct sunlight and moisture

•  Keep container tightly sealed when not in use

•  Wear gloves and avoid inhalation or contact with eyes/skin during handling

•  Do not reuse empty containers

•  Keep out of reach of children and unauthorized personnel

•  HS Code: 2934.99 — Other heterocyclic compounds

•  HSN Code (India): 2934 — Anthelmintics and veterinary parasiticides

•  Use only under veterinary supervision

•  Do not exceed recommended dosage

•  Avoid use in severely debilitated or stressed animals

•  Not recommended for animals under 4 weeks of age unless prescribed

•  Rotate with other classes of anthelmintics to prevent resistance

•  For Veterinary Use Only

•  Not for human use or consumption

•  Levamisole is restricted to veterinary applications and must be handled with care

•  Avoid contact with skin, eyes, or mucous membranes

•  In case of accidental ingestion or exposure, seek immediate medical advice

•  Strictly observe the withdrawal period to maintain food safety standards

Q: What is Levamisole Hydrochloride (LVH)?

A: Levamisole Hydrochloride (LVH) is a synthetic anthelmintic drug used in veterinary medicine to treat infections caused by gastrointestinal and lungworms in various animal species.

Q: How does Levamisole work?

A: It stimulates nicotinic receptors in parasites, causing muscle paralysis and expulsion through the intestines. It also has mild immunostimulant effects in animals.

Q: What types of animals can this be used for?

A: It is safe and effective in poultry, cattle, sheep, goats, and pigs when used at prescribed doses.

Q: Can I mix this powder in drinking water?

A: Yes. It is water-soluble and can be safely administered via drinking water or feed, ensuring accurate dosing.

Q: What is the withdrawal period for food-producing animals?

A: At least 7 days for meat and 3 days for milk. Always check and follow local regulatory guidelines.

Q: Are there any side effects?

A: Side effects are rare and usually mild. Overdose may cause cholinergic symptoms such as muscle tremors or hypersalivation.

Q: How should this product be stored?

A: Store in a dry place below 30°C, away from direct sunlight and moisture. Always reseal the container after use.