This veterinary bolus combines Aceclofenac I.P. (300 mg), a non-steroidal anti-inflammatory drug (NSAID), with Paracetamol I.P. (1500 mg), an analgesic-antipyretic. The formulation is designed for large animals to provide dual-action relief from pain, inflammation, and fever, particularly in conditions like musculoskeletal injuries, mastitis, pneumonia, and post-surgical recovery.

Composition per bolus:

•  Aceclofenac I.P. – 300 mg

•  Paracetamol I.P. – 1500 mg

•  Excipients – q.s.

Excipients may include: Microcrystalline cellulose, maize starch, croscarmellose sodium, magnesium stearate, lactose, and film-coating agents, all I.P.-grade and suitable for veterinary use.

Dosage Form: Solid Oral Veterinary Bolus

Appearance: Oblong, white or off-white bolus; smooth surface; may be embossed or coated.

Pharmacological Class:

•  Aceclofenac: Non-Steroidal Anti-Inflammatory Drug (NSAID)

•  Paracetamol: Antipyretic and Analgesic

Therapeutic Class:

•  Antipyretic

•  Analgesic

•  Anti-inflammatory

Indicated for:

•  Fever (Pyrexia) of bacterial or viral origin

•  Pain relief in musculoskeletal disorders (lameness, joint swelling)

•  Inflammatory conditions such as mastitis, metritis, or pneumonia

•  Post-surgical recovery (dehorning, castration, etc.)

•  Supportive therapy in infectious diseases with inflammation or fever

Suitable for cattle, buffalo, sheep, goats, and other large ruminants under veterinary guidance.

•  Dosage Form: Veterinary Oral Bolus

•  Pack Size: 10 × 4 (40 boluses per box; 4 boluses per strip)

•  Outer Box: Printed laminated carton with product info and storage conditions

•  Target Species: Cattle, Buffalo, Large Ruminants

Route: Oral

Recommended Dosage:

•  Large animals (Cattle, Buffalo): 1 bolus twice daily for 2–3 days, or as directed by the veterinarian

•  Small ruminants (Sheep, Goat): Dosage adjusted based on body weight

•  Administer whole bolus using a bolus applicator or manually

•  Fast-acting pain relief and anti-inflammatory action

•  Reduces fever, swelling, and general discomfort

•  Improves feed intake, mobility, and recovery speed

•  Combines two synergistic actives for broader therapeutic coverage

•  Fewer side effects compared to standalone NSAIDs

Usually well tolerated. Possible rare side effects include:

•  Gastrointestinal irritation or ulceration (especially with prolonged use)

•  Reduced appetite or lethargy

•  Hypersensitivity reactions (rash, swelling)

•  Renal stress in dehydrated animals (use with caution)

•  Use with caution in animals with liver or kidney disorders

•  Avoid concurrent administration with other NSAIDs or corticosteroids

•  Ensure animals are hydrated before and during treatment

•  Do not exceed the recommended dose

•  Not recommended for pregnant or lactating animals without veterinary supervision

•  Meat: Minimum 7 days after last dose

•  Milk: Minimum 3 days (Confirm based on local veterinary regulations)

Maintain proper treatment records and observe full withdrawal periods to ensure food safety compliance.

•  Store in a cool, dry place, below 30°C

•  Keep away from direct sunlight, heat, and moisture

•  Keep out of reach of children and non-target species

•  Do not use after the expiry date mentioned on the label

•  Use gloves during administration

•  Wash hands thoroughly after use

•  Do not break or crush the bolus/ Dispose of unused bolus as per local veterinary waste management guidelines

•  Schedule H equivalent (Prescription-only veterinary product)

•  Regulated under the Drugs and Cosmetics Act, India, or respective country’s veterinary authority

•  To be used only under the supervision of a registered veterinarian

•  HS Code (International): 3004.90 – Medicaments for veterinary use

•  HSN Code (India): 30049099 – Other veterinary medicaments not elsewhere classified

Veterinary Use Only

•  Dosage and excipients tailored for ruminant physiology

•  Not intended for human use under any condition

•  Human exposure may lead to incorrect dosing, liver stress, or allergic reactions

•  Always administer under veterinary direction

•  Do not repeat treatment cycles without reassessment

•  Ensure animals are eating and hydrated before treatment

•  Combine with antibiotics or antiparasitic drugs if indicated for infection

Q: What is the role of Aceclofenac in this bolus?

A: Aceclofenac is an NSAID used to relieve inflammation and pain in animals, particularly in joint, muscular, or post-surgical conditions.

Q: What does Paracetamol do in veterinary use?

A: Paracetamol is a fast-acting antipyretic (fever reducer) and mild analgesic, enhancing the comfort and healing process.

Q: Can this bolus be used in pregnant animals?

A: Avoid use in pregnant or lactating animals unless absolutely necessary and prescribed by a veterinarian.

Q: How soon does it act?

A: Onset of action is typically within 1–2 hours, with peak relief in 4–6 hours post-administration.

Q: Can this be given along with antibiotics?

 A: Yes — it is often prescribed alongside antibiotics to manage fever and inflammation during bacterial infections.

Q: Is this bolus safe for long-term use?

A: No — it is intended for short-term symptomatic relief. Prolonged use may risk GI irritation or renal stress.