Ivermectin is a broad-spectrum antiparasitic agent belonging to the ivermectin family. It is effective against a wide range of internal and external parasites in animals, including nematodes, arthropods, and certain ectoparasites. Ivermectin acts by binding selectively to glutamate-gated chloride ion channels in nerve and muscle cells of invertebrates, leading to paralysis and death of the parasites.

The product is formulated as a sterile injectable solution, available in amber glass vials of 10 ml and 100 ml, designed to ensure stability and protection from light.

•  Active Ingredient: Ivermectin 20 mg per ml (equivalent to 2%)

•  Excipients:

o   Propylene glycol (solvent)

o   Benzyl alcohol (preservative)

o   Water for Injection (vehicle)

•  pH adjusted for stability and compatibility with injection use

•  Appearance: Clear, colourless to slightly yellow sterile solution

•  Assay: Not less than 90% and not more than 110% of labelled ivermectin content

•  Sterility: Must be sterile as per pharmacopeial standards (USP/BP)

•  pH: 4.5 – 7.5

•  Free from visible particulate matter

•  Pyrogen-free as per regulatory guidelines

Ivermectin 20 mg injection is indicated for the treatment and control of:

•  Gastrointestinal roundworms (nematodes)

•  Lungworms (Dictyocaulus spp.)

•  Warbles (Hypoderma spp.)

•  Mange mites (Sarcoptes, Demodex)

•  Lice infestations in cattle, sheep, goats, and swine

•  Recommended dose: 0.2 mg ivermectin per kg body weight (equivalent to 1 ml per 100 kg) administered as a subcutaneous injection.

•  Administration route: Subcutaneous (under the skin) injection only. Avoid intravenous or intramuscular routes.

•  Dosage frequency: Single dose usually sufficient; consult veterinary advice for repeated treatment in heavy infestations.

Sterile injectable solution supplied in amber glass vials in two sizes:

•  10 ml vial (for small animals or precision dosing)

•  100 ml vial (for larger herds or extended use)

•  Broad-spectrum efficacy against internal and external parasites

•  Long-lasting effect with single dose administration

•  Easy-to-use injection form with accurate dosing

•  Minimal risk of resistance when used as directed

•  Safe in a wide range of domestic animals

•  Mild transient swelling or pain at the injection site may occur

•  Rarely, neurological signs in sensitive breeds (e.g., certain dog breeds with MDR1 gene mutation)

•  Overdose can cause tremors, ataxia, or coma—seek veterinary intervention immediately

•  Meat and offal: Minimum 28 days before slaughter for human consumption

•  Milk: Do not use in lactating animals producing milk for human consumption

•  Follow local regulatory guidelines strictly

•  For veterinary use only; not for human use

•  Keep out of reach of children

•  Use sterile needles and syringes for each injection to prevent contamination

•  Avoid use in animals with known hypersensitivity to ivermectin or excipients

•  Store away from direct sunlight and excessive heat

•  Store at 15°C to 30°C (59°F to 86°F) in a dry place

•  Protect from light by keeping in amber vial

•  Do not freeze

•  Keep vial tightly closed when not in use

•  Wear protective gloves when handling to avoid skin contact

•  In case of accidental human exposure, seek medical advice immediately

•  Dispose of empty vials and syringes as per local biohazard regulations

•  Avoid environmental contamination with unused product or packaging

•  HS Code: 3004.90 (Medicaments consisting of mixed or unmixed products for therapeutic or prophylactic uses, put up in measured doses or in forms or packings for retail sale)

•  HSN Code: 3004 (Medicaments consisting of mixed or unmixed products for therapeutic or prophylactic uses)

•  Do not administer intravenously or intramuscularly; only subcutaneous route is safe and effective

•  Always calculate dose carefully based on animal weight

•  Avoid using ivermectin in aquatic animals as it is toxic to fish

•  Monitor treated animals for adverse reactions for 24 hours post-injection

•  Ivermectin is approved widely for veterinary use to control parasites in livestock and companion animals

•  Human use ivermectin formulations exist but differ significantly in concentration and excipients—never substitute veterinary product for human use

•  Veterinary ivermectin is vital for animal health, food safety, and parasite management programs

Q1: What is Ivermectin (IVM)?

A: Ivermectin is a broad-spectrum antiparasitic drug used in veterinary and human medicine to treat parasitic infections.

Q2: Can I use this ivermectin injection for pets like dogs and cats?

A: This formulation is primarily for livestock animals. Use veterinary-approved formulations specifically designed for pets, under veterinary supervision.

Q3: How soon after injection can animals return to grazing or milking?

A: Withdrawal period for meat is 28 days; avoid milking animals during treatment and follow local regulatory guidelines.

Q4: What if I overdose the animal?

A: Signs may include tremors, drooling, or lethargy. Contact a veterinarian immediately for supportive care.

Q5: Is ivermectin safe during pregnancy?

A: Use with caution; consult a veterinarian before administration in pregnant or lactating animals.

Q6: How should I store this product?

A: Store between 15-30°C in a dry, light-protected place, and avoid freezing.