Tylosin is a macrolide antibiotic derived from Streptomyces species, widely used in veterinary medicine for its effectiveness against gram-positive bacteria and some mycoplasma species. The 20% injectable formulation contains tylosin base dissolved in a suitable solvent, designed for intramuscular or intravenous administration to treat bacterial infections in livestock.

Tylosin works by inhibiting bacterial protein synthesis, thus preventing the growth and proliferation of susceptible pathogens.

•  Active Ingredient: Tylosin base 20% w/v (200 mg/ml)

•  Excipients: Suitable solvents and stabilizers as per pharmacopeial standards

•  Packaged in 100 ml amber glass vial for protection against light

•  Appearance: Clear to slightly yellowish sterile solution

•  Assay: 90% – 110% of labelled tylosin content

•  Sterility: Complies with I.P./USP/BP sterility standards

•  pH: Approximately 4.5 – 6.5

•  Free from visible particulates and pyrogens

•  Treatment of respiratory, enteric, and soft tissue infections caused by tylosin-sensitive bacteria in cattle, swine, poultry, sheep, and other food-producing animals

•  Control of mycoplasmas and other bacterial infections responsive to macrolides

•  Adjunct therapy in bacterial infections resistant to other antibiotics

•  Dosage: Generally 4–10 mg tylosin base per kg body weight per day, depending on species and severity of infection

•  For 20% solution, this corresponds to 0.2–0.5 ml per kg body weight

•  Route: Intramuscular or intravenous injection, as directed by a veterinarian

•  Duration: Typically 3–5 days or as prescribed

Sterile injectable solution supplied in 100 ml amber glass vial to maintain product stability and potency

•  Broad-spectrum macrolide antibiotic effective against common veterinary pathogens

•  Suitable for use in multiple animal species

•  High concentration formulation allows accurate dosing and minimal injection volume

• Useful in respiratory and enteric infections, improving animal health and productivity

•  Local injection site reactions such as pain, swelling, or abscess formation

•  Rare hypersensitivity or allergic reactions

•  Use with caution in animals with known macrolide sensitivity

•  Avoid intravenous injection in horses due to risk of severe reactions

•  Meat: Minimum 28 days withdrawal period before slaughter

•  Milk: 10 days withdrawal period after last administration

•  Follow local veterinary guidelines strictly

•  For veterinary use only

•  Use aseptic technique during administration

•  Avoid extravasation during injection to reduce tissue irritation

•  Not for use in animals intended for human consumption without observing withdrawal times

•  Store vial tightly sealed and protected from light

•  Store at 15°C to 30°C (59°F to 86°F)

•  Protect from direct sunlight and freezing

•  Keep vial sealed until use

•  Wear gloves while handling and administering

•  Avoid accidental self-injection

•  Dispose of used vials and syringes safely according to biohazard protocols

•  HS Code: 2941.20 (Antibiotics)

•  HSN Code: 2941 (Antibiotics and other organic compounds)

•  Strictly follow veterinary prescription and dosing recommendations

•  Monitor animals for adverse effects during treatment

•  Maintain treatment records and observe withdrawal periods to ensure food safety

•  Tylosin is a veterinary antibiotic; human formulations differ and are not interchangeable

•  Essential in managing bacterial infections in food-producing animals to ensure herd health

•  Helps reduce reliance on critically important antibiotics by targeting specific pathogens

Q1: What is Tylosin 20% Injection?

 A: A macrolide antibiotic injection used to treat bacterial infections in animals.

Q2: How is it administered?

A: By intramuscular or intravenous injection under veterinary supervision.

Q3: What animals can receive this medication?

 A: Commonly cattle, swine, poultry, sheep, and other food animals.

Q4: Are there side effects? A: Possible injection site pain and rare allergic reactions.