Diethylstilboestrol (DES) is a synthetic non-steroidal estrogen used in veterinary practice for hormonal regulation, especially in large animals. This sterile oily injection contains 10 mg/mL of DES, formulated in an oily vehicle to ensure prolonged action. It is particularly effective in estrus induction, management of reproductive disorders, and selected therapeutic interventions under strict veterinary supervision.

•  Diethylstilboestrol U.S.P. – 10 mg

•  Oily Base I.P. – q.s. to 1 mL (sterile, long-acting carrier)

Synthetic Estrogenic Hormonal Agent – used for reproductive management and estrogen therapy in livestock.

•  Form: Sterile oily solution

•  Colour: Clear, pale yellow to light amber

•  Vehicle: Oil-based for sustained release

•  Sterility: Complies with USP injectable standards

•  Presentation: 10 ml multi-dose amber vial with rubber stopper and aluminium seal

•  Induction of estrus in anoestrous animals

•  Treatment of retained placenta, pyometra, or metritis

•  Management of urinary incontinence (in dogs, off-label)

•  Hormonal therapy in certain postpartum complications

•  Growth promotion (not recommended in many jurisdictions)

•  Cattle/Buffalo: 5–10 mg per animal (0.5–1 mL)

•  Dogs (if applicable): 0.1–0.5 mg/kg (use with extreme caution)

•  Route: Intramuscular (IM) injection only

•  Frequency: As directed by veterinarian — typically a single dose or short course

•  Pack Size: 10 ml multi-dose vial

•  Sterile oily injectable solution

•  Supplied in 10 ml amber glass vial

•  Multiple-dose vial with resealable rubber stopper

•  Reliable estrogenic response in target animals

•  Long-acting due to oily formulation

•  Effective in treating certain reproductive dysfunctions

•  Assists with estrus induction protocols

•  Supports hormonal balance in non-cycling females

•  Prolonged estrus, infertility, or ovarian cysts with misuse

•  Bone marrow suppression (esp. in small animals with chronic use)

•  Increased risk of neoplasia with long-term or repeated dosing

•  Use in food-producing animals is banned/restricted in many countries

•  Meat & Milk: Usage may be prohibited or require extended withdrawal periods Always check local regulations or consult a licensed veterinarian.

•  Store below 25°C

•  Protect from light and freezing

•  Shake gently before use

•  Use sterile syringe for each withdrawal

•  Discard unused product after expiry or contamination

•  For veterinary use only

•  Administer only under veterinary supervision

•  Not for use in animals intended for human consumption in many jurisdictions

•  Handle with gloves — avoid skin contact

•  Pregnant women should avoid handling this product

•  HS Code: 30049099

•  HSN Code: 3004

•  Strictly veterinary only

•  Not for human use – accidental exposure should be avoided

•  Use in companion animals should be limited and justified

•  Q1: What is Diethylstilboestrol used for in animals?

It is a synthetic estrogen used to regulate estrus, treat reproductive issues, or manage hormonal imbalances.

•  Q2: Can it be used in food animals?

No. Use in food-producing animals is banned in many countries due to carcinogenic potential and residue concerns.

•  Q3: Is DES safe in dogs?

 It may be used in very low doses for urinary incontinence, but only under strict veterinary supervision due to potential toxicity.

•  Q4: How is it stored?

Keep in a cool, dry place away from sunlight. Do not refrigerate or freeze.

•  Q5: Any handling precautions?

Yes, always wear gloves. Pregnant women should avoid handling the product.